Casandra
Casandra Test Code AR98737Version 1 (DRAFT)
Performing Lab
Mutated Citrullinated Vimentin (MCV) Antibody, Serum (Change effective as of 04/21/25: Refer to 3019462 in the April Hotline)
Also known as: MCV AB
Clinical Use
Order TestUse
Used as an aid in the diagnosis of rheumatoid arthritis (RA) in conjunction with other laboratory and clinical findings; anti‑MCV antibodies can be found in some patients negative for anti‑CCP antibodies, may indicate early RA, correlate with disease activity, and poor radiographic prognosis.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Mutated Citrullinated Vimentin (MCV) antibody
ProteinConcentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
Not provided
Minimum Volume
0.5 mL
Container
Serum separator tube (SST)
Collection Instructions
Separate serum from cells as soon as possible or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube.
Causes for Rejection
Contaminated, heat‑inactivated, grossly hemolyzed, grossly icteric, or grossly lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hour |
| Refrigerated | 5 days |
| Frozen | 30 days |