PML-RARA Detection by RT-PCR, Quantitative (Test on Referral as of 1/17/2023) (Change effective as of 01/20/26: Refer to 3018922 in the January Hotline)
Also known as: PML QNT
Use
Use to detect and quantitate PML::RARA fusion transcripts in individuals with acute promyelocytic leukemia; used to monitor minimal residual disease and assess the risk of relapse ([ltd.aruplab.com](https://ltd.aruplab.com/Tests/Pub/3018922?utm_source=openai))
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
PCR-based (RT-PCR)
Biomarkers
LOINC Codes
- 66746-9
- 21551-7
- 21785-1
Result Turnaround Time
2-9 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL whole blood (Min: 3 mL)
Minimum Volume
3 mL
Container
lavender (EDTA)
Collection Instructions
Collect whole blood in lavender (EDTA). Refrigerate immediately. Specimens must be received within 48 hours of collection due to lability of RNA. ([ltd.aruplab.com](https://ltd.aruplab.com/Tests/Pub/3018922?utm_source=openai))
Storage Instructions
CRITICAL REFRIGERATED
Causes for Rejection
Serum, plasma, extracted DNA, CSF, FFPE tissue, ambient whole blood, or frozen whole blood or bone marrow; anticoagulants other than EDTA; severely hemolyzed or clotted specimens; specimens received >7 days post collection will be canceled ([ltd.aruplab.com](https://ltd.aruplab.com/Tests/Pub/3018922?utm_source=openai))
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 48 hours |
| Frozen | Unacceptable |