Saccharomyces cerevisiae Antibodies, IgG & IgA
Also known as: SC PAN
Use
Saccharomyces cerevisiae antibodies may aid in the diagnosis of Crohn disease. The test should be used in conjunction with other clinical parameters to confirm the disease. Saccharomyces cerevisiae IgG antibodies are found in 60-70% of Crohn disease patients and 10-15% of ulcerative colitis patients. IgA antibodies are found in about 35% of Crohn disease patients and less than 1% of ulcerative colitis patients. Detection of both IgG and IgA antibodies is highly specific for Crohn disease, which can help distinguish it from ulcerative colitis.
Special Instructions
Not provided.
Limitations
This test, by itself, is not diagnostic and should not be used as the sole method for diagnosing Crohn disease. The presence of antibodies should be interpreted in conjunction with clinical findings and other laboratory tests to establish the diagnosis of inflammatory bowel disease. False positives or negatives may occur, and the presence of antibodies in other conditions can affect specificity.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 47321-5 - Baker's yeast IgG Qn IA
- 47320-7 - Baker's yeast IgA Qn IA
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection and transfer to transport tube.
Storage Instructions
Refrigerated storage is required. Ambient stability is 48 hours, refrigerated stability is 2 weeks, and frozen stability is 1 year (avoid repeated freeze/thaw cycles).
Causes for Rejection
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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