SOX1 Antibody, IgG by Immunoblot, CSF
Also known as: SOX1 CSF
Use
SOX1 antibody is primarily used for detecting Lambert-Eaton myasthenic syndrome (LEMS) and paraneoplastic cerebellar degeneration (PCD). It is associated with occult tumors, recurrence of tumors, or the presence of second tumors, particularly with small cell lung cancer. A negative result does not rule out LEMS or other paraneoplastic neurological syndromes.
Special Instructions
Serum is the preferred specimen type for SOX1 antibody testing. Consider ordering serum tests when applicable. The test is reported 1 to 4 days after performance on Mon, Thu, and Sat.
Limitations
This qualitative immunoblot test does not provide a quantitative measure of the SOX1 antibody level. A negative result in this test does not completely exclude the diagnosis of LEMS or other paraneoplastic neurological syndromes. Potential interferences include contaminated, heat-inactivated, hemolyzed, or lipemic specimens, which can be rejected.
Methodology
Immunoassay (Western Blot)
Biomarkers
LOINC Codes
- 94383-7
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1 mL
Minimum Volume
0.60 mL
Container
ARUP Standard Transport Tube
Storage Instructions
Refrigerated.
Causes for Rejection
Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
