Paraneoplastic Autoantibody Profile, Spinal Fluid
Also known as: Autoimmune Paraneoplastic Panel, Paraneoplastic CSF, Paraneoplastic Syndrome Test
Use
This test is used for the detection of antineuronal autoantibodies that help in the diagnosis of paraneoplastic syndromes.
Special Instructions
Not provided.
Limitations
A negative paraneoplastic autoantibody result does not rule out all clinically relevant antibodies. Additional phenotype-specific profiles (for encephalopathy, dementia, myelopathy, or axonal neuropathy) may be required for comprehensive evaluation. This test has not been cleared or approved by the Food and Drug Administration and operates under CLIA requirements.
Methodology
Immunoassay (Immunofluorescence)
Biomarkers
LOINC Codes
- 94818-2 - Paraneoplastic Ab Pnl CSF IF
- 56850-1 - Imp & review of lab results
- 44768-0 - Hu1 Ab CSF Ql IF
- 56959-0 - Hu2 Ab CSF Ql IF
- 90836-8 - Hu3 Ab CSF Ql IF
- 14247-1 - Purkinje Cells Ab CSF Ql IF
- 90843-4 - PCA-2 Ab CSF Ql IF
- 90845-9 - PCA-Tr Ab CSF Ql IF
- 90815-2 - Amphiphysin Ab CSF Ql IF
- 63216-6 - CV2 Ab CSF Ql IF
- 90827-7 - Glial nuc type 1 Ab CSF Ql IF
- 90820-2 - CASPR2 Ab CSF Ql CBA IFA
- 90830-1 - LGI1 Ab CSF Ql CBA IFA
Result Turnaround Time
4 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
2 mL
Minimum Volume
1 mL
Container
Sterile plastic tube
Storage Instructions
Room temperature
Causes for Rejection
Gross hemolysis; grossly lipemic; gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant