SOX1 Antibody, IgG by Immunoblot, Serum
Also known as: SOX1 SER
Use
The SOX1 antibody test is useful in assessing patients for Lambert-Eaton myasthenic syndrome (LEMS), paraneoplastic cerebellar degeneration (PCD), or paraneoplastic and nonparaneoplastic neuronopathy. It aids in the detection of associated occult tumors, tumor recurrence, or a second tumor. This test detects the presence of SOX1 antibodies, which are associated with small cell lung cancer.
Special Instructions
Only serum specimens are accepted. Ensure that serum is separated from cells as soon as possible, preferably within two hours of collection, and transferred to an ARUP Standard Transport Tube.
Limitations
A negative result does not rule out the presence of Lambert-Eaton myasthenic syndrome or other causes of paraneoplastic neurological syndromes. As this is a qualitative test, it may not quantify the antibody levels accurately. It has not been cleared or approved by the FDA and is for clinical purposes performed in a CLIA-certified laboratory.
New York Approved
Methodology
Immunoassay (Western Blot)
Biomarkers
LOINC Codes
- 82444-1
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.30 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerate after collection. Do not freeze before separation.
Causes for Rejection
Plasma. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |