Testosterone, Free and Total, by Dialysis and Mass Spectrometry (Adult Males or Individuals on Testosterone Hormone Therapy)
Also known as: TE F&T ED
Use
This test is used for the direct measurement of free testosterone in adult males or individuals on testosterone hormone therapy. It is crucial for monitoring testosterone levels due to its accurate measurement using equilibrium dialysis and mass spectrometry, making it valuable for clinical assessments of testosterone-related disorders or hormone therapy adjustments. Not recommended for low testosterone concentrations typically seen in children or cisgender females.
Special Instructions
Testing should be performed between 6-10 a.m. to ensure accurate measurement due to the diurnal variation in testosterone levels. This test is not recommended when low concentrations of free testosterone are expected, as seen in children and cisgender females. Preferred alternative tests are provided for these groups.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration. It is suitable for adult males and individuals on testosterone hormone therapy but not recommended for those with expected low testosterone concentrations, such as children and cisgender females. Reference intervals are established for males 18 years and older, but not for females or males under 18.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 2991-8
- 2986-8
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Serum separator tube or green (sodium or lithium heparin)
Collection Instructions
Separate serum or plasma from cells ASAP or within 2 hours of collection.
Patient Preparation
Collect between 6-10 a.m.
Causes for Rejection
EDTA plasma.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 2 months |