Tropheryma whipplei PCR
Also known as: TWHIPPCR
Use
Tropheryma whipplei PCR is designed to aid in the diagnosis of Whipple disease, particularly in cases where other diagnostic methods are inconclusive or yield suspicious results. It is utilized as part of a comprehensive diagnostic approach to confirm the presence of Tropheryma whipplei, the bacterium responsible for the disease. The test is significant in clinical settings for providing clarity in complex diagnostic circumstances, facilitating appropriate patient management and treatment strategies.
Special Instructions
Not provided.
Limitations
While the Tropheryma whipplei PCR test is highly specific for detecting the presence of the bacterium, it does not exclude the possibility of PCR inhibitors in the patient specimen, which could lead to false-negative results. Additionally, the test may not detect nucleic acid concentrations below its level of detection. It is not FDA-approved but is a Laboratory Developed Test performed in a CLIA-certified lab, meant solely for clinical use. The results should be interpreted in conjunction with other clinical and laboratory data for accurate diagnosis.
New York Approved
Methodology
PCR-based (Qualitative Polymerase Chain Reaction)
Biomarkers
LOINC Codes
- 31208-2 - Specimen source
- 46725-8 - T whipplei DNA Spec Ql NAA+probe
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.5 mL
Container
Lavender (EDTA), Pink (K2EDTA)
Collection Instructions
Collect specimen in appropriate tube, transfer to sterile container.
Storage Instructions
Specimens, except FFPE, should be frozen for transport.
Causes for Rejection
Heparinized specimens, tissues in optimal cutting temperature compound.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
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