Amantadine, Serum or Plasma
Also known as: Symmetrel®
Use
Therapeutic drug management
Special Instructions
Not provided.
Limitations
Therapeutic range has not been established; expected steady‑state concentrations in patients receiving recommended daily dosages are cited (200–1000 ng/mL), but individual variability and lack of formal reference range limit interpretive certainty.
Methodology
Mass Spectrometry
Biomarkers
Amantadine
Analyte
LOINC Codes
- 3317-5 - Amantadine SerPl-mCnc
- 3317-5 - Amantadine SerPl-mCnc
Result Turnaround Time
10-14 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
1.2 mL
Container
Red‑top tube or green‑top (heparin) tube; gel‑barrier tubes are not recommended
Collection Instructions
Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.
Patient Preparation
Trough levels are most reproducible.
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
Causes for Rejection
Gel‑barrier tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 21 days |
| Refrigerated | 21 days |
| Frozen | 4 weeks |
Other tests from different labs that may be relevant