Anti-Contactin-Associated Protein-2 (CASPR2), Serum
Use
The Anti-Contactin-associated protein-2 (CASPR2) IgG antibody is part of the voltage-gated potassium channel (VGKC) complex antibodies. CASPR2 autoantibodies often occur in elderly males, and patients with these antibodies commonly present with conditions such as neuromyotonia, Morvan's syndrome, limbic encephalitis, and neuropathic pain syndromes. This test aids in diagnosing CASPR2 antibody-related disorders and is valuable for managing antibody-positive individuals following immunotherapy and/or plasmapheresis.
Special Instructions
Not provided.
Limitations
Results should not be used as a diagnostic procedure without confirmation by another medically established product or procedure. The test's performance characteristics were determined by Labcorp and it has not been cleared or approved by the Food and Drug Administration.
Methodology
Immunoassay (Immunofluorescence)
Biomarkers
CASPR2 IgG Antibody
Protein
LOINC Codes
- 90820-2 - CASPR2 Ab CSF Ql CBA IFA
- 82979-6 - CASPR2 IgG SerPl Ql IF
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Gel-barrier tube, red-top tube, serum gel tube, serum transfer tube
Storage Instructions
Room temperature
Causes for Rejection
CSF or plasma; contaminated, hemolyzed or severely lipemic specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant