Anti-ENA6 Plus DFS70Ab Profile

Casandra

Casandra Test Code LC09654Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 520301CPT Codes 83516, 86235

Anti-ENA6 Plus DFS70Ab Profile

Also known as: Anti-Extractable Nuclear Antigens (ENA) 6 Plus Anti-Dense Fine Speckled 70 Antibodies Profile

Clinical Use

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Use

Anti-ENA6 Plus DFS70 is designed to facilitate the proper triage of patients with positive Anti-Nuclear Antibodies (ANA) by identifying those most likely to benefit from a rheumatology specialist. It detects the novel Anti-DFS70 along with 6 other clinically useful autoantibodies to ENA, which may help identify systemic lupus erythematous (SLE), mixed connective tissue disease (MCTD), Sjogren's, systemic sclerosis, and idiopathic inflammatory myopathy (IIM). Positive Anti-DFS70 antibodies in isolation may help identify individuals who do not have an AARD (ANA-associated rheumatic disease), especially in the absence of significant clinical findings.

Special Instructions

Not provided.

Limitations

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. The presence of Anti-DFS70 Abs in isolation may help identify individuals who do not have AARD, especially in the absence of significant clinical findings. Anti-DFS70 Abs are detectable in 2% to 22% of healthy individuals and in less than 1% of patients with ANA-associated rheumatic disease.

Test Details