Anti-Ribosomal P Protein Ab (RDL)
Also known as: Anti-Ribosomal P Protein Ab, RPPA
Use
Ribosomal P antibodies (RPPA) are detected in 45-90% of patients with severe depression or psychosis due to SLE; 7-20% in non-psychotic SLE patients. RPPA are ocasionally found in Sjorgen's syndrome associated with SLE and CNS complications and uncommon in patients with scleroderma and overlap with SLE.
Special Instructions
To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Limitations
The test may not distinguish between different conditions beyond those associated with SLE or scleroderma. Intrinsic assay variability and sample handling may affect results, leading to false positives or negatives in certain cases.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 13636-6
- 13636-6
Result Turnaround Time
7-14 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |