Anti-SRP Ab (RDL)
Also known as: Signal Recognition particle, SRP
Use
SRP is considered a Myositis-specific antibody. It is commonly found in Polymyositis, ILD and arthritis, and occasionally in dermatomyositis. Anti-SRP was first described in a polymyositis patient in 1986. Anti-SRP antibodies are rare, in only about 4% of myositis patients, and are often found in African American females with an acute, severe onset of polymyositis, with poor response to therapy.
Special Instructions
Not provided.
Limitations
This test was developed and its performance characteristics were determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Other
Biomarkers
Anti-SRP
Antibody
LOINC Codes
- 33921-8 - SRP Ab SerPl Ql
- 33921-8 - SRP Ab SerPl Ql
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, submit separate frozen specimens for each test requested.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |
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