Antiadrenal Antibodies, Quantitative
Also known as: Adrenal Antibodies, Serum, Antiadrenal Cortex Antibodies
Use
Evaluate for adrenal insufficiency and Addison disease. Serum antibodies to adrenal cortical cells, usually of all three zones, are seen in 60% of patients with idiopathic Addison disease. They are present in only 5% to 17% of patients with tuberculous, fungal, or metastatic destruction of the adrenals, and in 38% of unclassified cases. Antiadrenal antibodies are also present in such apparently unrelated processes as idiopathic hypoparathyroidism (28% of cases) and Hashimoto disease (7%).
Special Instructions
Not provided.
Limitations
This test has a defined reference range, with negative results indicated by titers of less than 1:10. As with all laboratory tests, the potential for false negatives or positives exists, and results should be interpreted in the context of the patient's clinical condition and history.
Methodology
Immunoassay (Indirect fluorescent antibody (IFA))
Biomarkers
Adrenal Antibody
Protein
LOINC Codes
- 5043-5 - Adrenal Ab Titr Ser IF
- 5043-5 - Adrenal Ab Titr Ser IF
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.6 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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