Azathioprine as 6-Mercaptopurine (6-MP), Serum or Plasma
Also known as: Azasan®, Imuran®
Use
Therapeutic drug management
Special Instructions
Not provided.
Limitations
Therapeutic and toxic reference ranges for serum 6‑mercaptopurine concentrations have not been established. Usual therapeutic dosing produces levels <1000 ng/mL, but interpretation must consider lack of validated target ranges.
Methodology
Mass Spectrometry
Biomarkers
6‑Mercaptopurine
Analyte
LOINC Codes
- 11242-5 - Mercaptopurine SerPl-mCnc
Result Turnaround Time
10-14 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
0.5 mL
Container
Red-top tube or green-top (heparin) tube; gel-barrier tubes not recommended
Collection Instructions
Trough levels are most reproducible. Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.
Patient Preparation
Trough levels are most reproducible.
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
Causes for Rejection
Gel-barrier tubes
Other tests from different labs that may be relevant