Breast Cancer Prognosis Profile II, Paraffin Block
Use
Provide prognostic information to aid the physician in determining risk of recurrence and potential benefits of therapy options for the breast cancer patient; HER-2/neu gene amplification status is a predictor of response to certain breast cancer treatments, including targeted immunotherapy.
Special Instructions
Not provided.
Limitations
Use of fixatives other than 10% formalin may not yield equivalent or satisfactory results.
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 74885-5 - ERBB2 (HER2) Dup Pnl Tiss FISH
- 18474-7 - Her2 Ag Tiss Ql ImStn
- 14228-1 - ER+ cells NFr Tiss ImStn
- 14230-7 - PR+ cells NFr Tiss ImStn
- 8251-1 - Service Cmnt-Imp
- 31150-6 - ERBB2 gene Dp Tiss Ql FISH
- 49683-6 - ERBB2 copy num/Chr 17 copy num Tiss FISH
- 74860-8 - ERBB2 copy num/nucleus EntNum Tiss FISH
- 74861-6 - Chr 17 copy num/nucleus EntNum Tiss FISH
- 62361-1 - Cells counted
- 19147-8 - Ref Lab Test Ref Range
Result Turnaround Time
5-6 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
One paraffin block
Minimum Volume
Not provided
Container
Paraffin block transport pouch
Collection Instructions
Specimen should be fixed in 10% neutral-buffered formalin. Optimum fixation time is 12 to 24 hours, not to exceed 48 hours.
Storage Instructions
Maintain specimen at room temperature.
Other tests from different labs that may be relevant