ERBB2 (HER2) (HercepTest)™ by Immunohistochemistry
Also known as: HERCEP IHC
Use
This immunohistochemistry (IHC) stain is provided as a technical “stain and return” service to evaluate ERBB2 (HER2) expression to assist in determining eligibility for HER2-directed therapies in relevant carcinomas.
Special Instructions
Not provided.
Limitations
Unacceptable conditions include non-representative tissue, depleted specimens, decalcified specimens, and frozen specimens. Frozen specimens are unacceptable; room temperature or refrigerated transport is acceptable.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
ERBB2 (HER2)
Protein
LOINC Codes
- 94736-6 - Tissue block ID Spec
- 18474-7 - Her2 Ag Tiss Ql ImStn
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
5 unstained (3‑ to 5‑micron thick) slides (min: 2 slides) or tissue block
Container
tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed; cells must be prepared into a cellblock; protect block/slides from excessive heat; do not oven bake precut slides
Storage Instructions
Room temperature or refrigerated; ship in cooled container during summer months
Causes for Rejection
Non‑representative tissue type; depleted specimens; decalcified specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant