Buprenorphine and Norbuprenorphine, Serum or Plasma
Also known as: Buprenex®, Free Buprenorphine, Subutex®
Use
Buprenorphine is used in the management of moderate to severe chronic pain.
Special Instructions
Not provided.
Limitations
The test was developed by Labcorp and has not been cleared or approved by the FDA. It measures buprenorphine concentrations for therapeutic management, but unspecified factors like patient variability, novel drug interactions, or sample contamination could affect accuracy. Results should not be the sole factor in therapeutic management but should be considered in conjunction with clinical evaluation.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 75368-1 - Buprenorphine SerPlBld-mCnc
- 75368-1 - Buprenorphine SerPlBld-mCnc
- 75370-7 - Norbuprenorphine SerPlBld-mCnc
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
3 mL
Minimum Volume
0.5 mL
Container
Red-top (no additive) tube or green-top (heparin) tube
Collection Instructions
Transfer separated serum or plasma to a plastic transport tube. Trough levels are most reproducible.
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
Causes for Rejection
Gel-barrier tubes are not recommended
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant