Casein
Use
The Casein test measures specific IgE antibodies to casein, which is one of the major proteins found in milk. This test is used to help confirm a casein allergy, which is a significant concern for individuals with cow's milk allergy. The presence of IgE antibodies to casein can trigger allergic reactions in sensitive individuals, making this test important for diagnostic purposes in allergen-specific IgE quantification.
Special Instructions
This test requires a serum sample collected in a red-top tube or gel-barrier tube. Ensure that the specimen is correctly labeled and stored according to the provided stability instructions to maintain integrity until testing is performed.
Limitations
The test is specific for IgE antibodies to casein and does not provide information about other components of milk or other potential allergens. The presence of IgE antibodies indicates sensitization but does not establish a clinical allergy diagnosis by itself. The test should be interpreted in the context of the patient's clinical history and additional testing as required. False positives and negatives can occur, and cross-reactivity with other milk proteins may impact results.
Methodology
Immunoassay (Thermo Fisher ImmunoCAP®)
Biomarkers
LOINC Codes
- 6062-4
- 6062-4
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.2 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 3 months |