Coagulation Screening Reflexive Evaluation
Use
Screening to support and direct the diagnosis of coagulation disorders
Special Instructions
The following reflex tests may be performed per profile specifications and/or pathologist discretion: Factor II Activity; Factor V Activity; Factor VII Activity; Factor X Activity; Factor VIII Activity, Factor IX Activity, Factor XI Activity; Prothrombin Time Mixing Studies; Activated Partial Thromboplastin Time Mixing Studies; Thrombin Time following Heparin Neutralization; Fibrinogen Activity; Fibrinogen Antigen; Reptilase; Anticardiolipin Antibody IgG and IgM; β2 Glycoprotein I IgG and IgM; Factor XII Activity; Prekallikrein (Fletcher Factor) Assay; High Molecular Weight Kininogen (Fitzgerald Factor). If reflex testing is performed, concomitant CPT codes/charges will apply.
Limitations
This test is subject to limitations such as potential interference from anticoagulant therapies. It is critical for patients to ideally not be on anticoagulant therapy prior to the test. Warfarin should be avoided for two weeks, and heparin, direct Xa, and thrombin inhibitor therapies should be avoided for three days prior to testing to minimize potential interferences that could affect the test’s diagnostic accuracy.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 98125-8
- 5902-2
- 6301-6
- 14979-9
- 3243-3
- 6303-2
- 57838-5
- 50410-0
- 3282-1
- 21026-0
Result Turnaround Time
3-10 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2.0 mL
Minimum Volume
Not provided
Container
Light blue-top (sodium citrate) collection tubes
Collection Instructions
Plasma must be separated from cells within 45 minutes of venipuncture, and centrifuged a second time before being placed in plastic transport tubes. Freeze plasma within two hours and keep frozen until testing is performed.
Patient Preparation
Ideally, the patient should not be on anticoagulant therapy. Avoid warfarin (Coumadin®) therapy for two weeks prior to testing. Avoid heparin, direct Xa and thrombin inhibitor therapies for three days prior to testing.
Storage Instructions
Freeze.