Creatine Kinase (CK), MB
Also known as: CK-2, CK-MB
Use
Confirm and monitor therapy after acute myocardial infarction
Special Instructions
Biotin (vitamin B7, B8) supplementation can interfere with the test results. Patients should refrain from biotin consumption for at least 72 hours before sample collection. It is recommended to ask all patients indicated for this test about biotin use.
Limitations
CK-MB levels might reflect skeletal muscle injury rather than myocardial damage. Surprisingly low baseline levels might be found in the elderly. Random single CK-MB measurements cannot definitively confirm or rule out AMI; serial measurements over time are advised in the emergency room setting and during treatment.
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 13969-1
- 13969-1
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.7 mL
Container
Gel-barrier tube (preferred) or red-top tube
Collection Instructions
If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage Instructions
Room temperature
Causes for Rejection
Citrate plasma specimen; improper labeling
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 day |
| Refrigerated | 14 days |
| Frozen | 14 days |