Creatine Kinase, MB
Also known as: CK MB
Use
The Creatine Kinase, MB test is essential for assessing muscle damage or myocardial infarction. It measures the MB isoenzyme of creatine kinase, which is predominantly found in heart muscle. Elevated levels may indicate heart muscle injury, making this test crucial in diagnosing acute coronary syndromes and other conditions that affect heart health. Troponin testing is recommended as a complementary test for diagnosis and management of acute coronary syndrome.
Special Instructions
Creatine Kinase, MB tests are quite labile. It is important to transfer the specimen to a transport tube and freeze it to ensure the accuracy of results. Ensure that the specimen is separated from cells as soon as possible and within two hours of collection.
Limitations
The test is labile and specimens containing particulate material or grossly hemolyzed samples are unacceptable. Results must be interpreted in conjunction with other clinical findings and complementary tests like Troponin T for comprehensive diagnosis. Temporary elevations can be seen following muscle injury or strenuous exercise, and elevation does not always indicate a cardiac event.
New York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 13969-1
- 13969-1
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Allow specimen to clot for 15-20 minutes at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer to an ARUP Standard Transport Tube.
Causes for Rejection
Specimens containing particulate material. Grossly hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 12 hours |
| Refrigerated | 72 hours |
| Frozen | 3 months |