Heparin-induced Platelet Antibody (HIPA)
Also known as: Heparin-associated Thrombocytopenia Antibody (HATA), Heparin-induced Thrombocytopenia (HIT), Heparin-induced Thrombocytopenia Antibody (HITA), Vaccine-Associated Coagulopathy, Vaccine-Induced Immune Thrombotic Thrombocytopenia
Use
Assist in the diagnosis of heparin-induced thrombocytopenia
Special Instructions
Not provided.
Limitations
HIPA results should not be the sole basis for establishing the diagnosis of heparin-induced thrombocytopenia. Microbial contamination, lipemia, icterus, or hemolysis may interfere with this test. Immune complexes or immunoglobulin aggregates in the patient sample can produce false-positive results. Heparin in the sample (>1 unit/mL) can produce false-negative results.
Methodology
Immunoassay (ELISA)
Biomarkers
Platelet factor 4 complexed polyvinyl sulfonate
Protein
LOINC Codes
- 73818-7 - PF4 heparin cmplx IgG SerPl IA
- 73818-7 - PF4 heparin cmplx IgG SerPl IA
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Transfer serum to a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze
Causes for Rejection
Serum not separated from red cells; microbially contaminated, hemolyzed, lipemic, icteric, or heat-inactivated samples
Other tests from different labs that may be relevant