Heparin-induced Platelet Antibody (HIPA)

Also known as: Heparin-associated Thrombocytopenia Antibody (HATA), Heparin-induced Thrombocytopenia (HIT), Heparin-induced Thrombocytopenia Antibody (HITA), Vaccine-Associated Coagulopathy, Vaccine-Induced Immune Thrombotic Thrombocytopenia

Clinical Use

Order Test

Use

Assist in the diagnosis of heparin-induced thrombocytopenia

Special Instructions

Not provided.

Limitations

HIPA results should not be the sole basis for establishing the diagnosis of heparin-induced thrombocytopenia. Microbial contamination, lipemia, icterus, or hemolysis may interfere with this test. Immune complexes or immunoglobulin aggregates in the patient sample can produce false-positive results. Heparin in the sample (>1 unit/mL) can produce false-negative results.

Test Details

Methodology

Immunoassay (ELISA)

Biomarkers

Platelet factor 4 complexed polyvinyl sulfonate

Protein

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

73818-7 - PF4 heparin cmplx IgG SerPl IA

Result Codes

73818-7 - PF4 heparin cmplx IgG SerPl IA

Result Turnaround Time

1-2 days

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

Red-top tube or gel-barrier tube

Collection Instructions

Transfer serum to a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.