Platelet Antibody Screen, Serum
Use
This test screens for platelet-associated antibodies (IgG, IgM, and possibly IgA) targeting HLA class I and platelet glycoprotein antigens (GP IIb/IIIa, Ib/IX, Ia/IIa, and GP IV). It is useful in evaluating platelet refractoriness following transfusion or pregnancy and in the diagnosis of neonatal alloimmune thrombocytopenia (NAIT) and post–transfusion purpura. Results patterns should not be used as the sole clinical basis for decision-making. Quest performs in‑lab verification under CLIA/CAP guidance. ([questdiagnostics.com](https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq195?utm_source=openai))([shermanabrams.com](https://www.shermanabrams.com/5115-2/?utm_source=openai))
Special Instructions
Not provided.
Limitations
The results should not be used as the sole basis for a clinical decision; reaction patterns alone are not sufficient to establish platelet antibody identity. ([questdiagnostics.com](https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq195?utm_source=openai))
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 47084-9 - Plat Gp Ia/IIa Ab Ser Ql IA
- 48506-0 - Plat Gp Ib/Ix Ab Ser Ql IA
- 48505-2 - Plat Gp IIb/IIIa Ab Ser Ql IA
- 87757-1 - Plat Gp IV Ab SerPl Ql IA
- 95269-7 - HLA-A+B+C Ab SerPl Ql IA
- 59466-3 - Hematologist review
- 24375-8 - Platelet Ab Ser Ql
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Container
Red tube
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 48 hours |
| Frozen | 1 year |
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