Protein Electrophoresis, Serum
Also known as: Electrophoresis, Serum
Use
A principal use of this test is in the detection of monoclonal gammopathies. These are usually found in association with hemic neoplasms, especially multiple myeloma. They also occur in other benign and malignant conditions. Any such protein detected should be identified by an alternative technique, such as immunofixation or immunoelectrophoresis.
Special Instructions
Not provided.
Limitations
In evaluating multiple myeloma, 12% of patients may not be detected by serum protein electrophoresis alone. Therefore, the addition of serum free light chains and immunofixation increases detection to over 99% in line with recommended guidelines. Absolute values should be used for interpretation rather than relative percentages.
Methodology
Other
Biomarkers
LOINC Codes
- 24351-9 - Prot Elph Pnl SerPl
- 2885-2 - Prot SerPl-mCnc
- 2862-1 - Albumin SerPl Elph-mCnc
- 2865-4 - Alpha1 Glob SerPl Elph-mCnc
- 2868-8 - Alpha2 Glob SerPl Elph-mCnc
- 2871-2 - B-Globulin SerPl Elph-mCnc
- 2874-6 - Gamma glob SerPl Elph-mCnc
- 33358-3 - M Protein SerPl Elph-mCnc
- 10834-0 - Globulin Ser Calc-mCnc
- 1759-0 - Albumin/Glob SerPl
- 77202-0 - Laboratory comment Report
- 11502-2 - Laboratory report
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate at 2°C to 8°C.
Causes for Rejection
Hemolysis; plasma instead of serum
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 3 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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