Protein Electrophoresis and Kappa/Lambda Light Chains
Use
Serum protein electrophoresis (SPE) provides separation of serum proteins into six fractions—Albumin, Alpha‑1, Alpha‑2, Beta‑1, Beta‑2, and Gamma. Changes in these fractions (elevations, decreases, or visual alterations) can aid in diagnosing a variety of diseases and protein abnormalities, including monoclonal gammopathies (MG). Measurement of total kappa and lambda light chains and their ratio further assists in the evaluation of monoclonal protein disorders. (References: QC laboratory details) ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/cmclab/test/1118898?utm_source=openai))
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Other
Biomarkers
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
5 mL
Minimum Volume
1.6 mL
Container
Transport tube
Patient Preparation
Overnight fasting is preferred
Causes for Rejection
Gross hemolysis • Grossly lipemic • Grossly icteric • Plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 7 days |
| Frozen | 28 days |
Other tests from different labs that may be relevant