Syphilis: RPR With Reflex to RPR Titer
Also known as: Nontreponemal, Rapid Plasma Reagin, RPR
Use
This test can be used to follow treatment response in patients being treated for syphilis infection. This assay should not be used to screen for syphilis infection. To screen for syphilis infection, a reflex cascade that includes both RPR and a treponema-specfic assay should be utilized, such as Treponema pallidum (Syphilis) Screening Cascade [082345] or Rapid Plasma Reagin (RPR) Test With Reflex to Quantitative RPR and Confirmatory Treponema pallidum Antibodies [012005]. See Related Information to view these tests.
Special Instructions
Not provided.
Limitations
This test is not intended for screening purposes and should not be used as a primary diagnostic test for syphilis infection. It is important to note that nontreponemal tests such as RPR can produce false-positive results due to other conditions and require confirmation with a treponemal test. Additionally, biological false nonreactive results can occur in patients with compromised immunocompetence or early in the course of infection before seroconversion.
Methodology
Other
Biomarkers
Rapid Plasma Reagin
Analyte
LOINC Codes
- 20507-0 - RPR Ser Ql
- 20507-0 - RPR Ser Ql
- 31147-2 - RPR Ser-Titr
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Grossly hemolyzed; grossly lipemic; gross bacterial contamination; plasma specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant