Apolipoprotein E (ApoE) Isoform, CSF
Also known as: Amyloid imaging abnormalities, Alzheimer's Disease (AD), ApoE2, ApoE3, ApoE4
Use
This LC‑MS/MS assay identifies the ApoE isoform(s) in cerebrospinal fluid, aiding in the assessment of Alzheimer’s disease likelihood.
Special Instructions
Not available for individuals under age 18. Pre‑test and post‑test counseling strongly recommended.
Limitations
Specimens collected in inappropriate containers (e.g., glass, polystyrene, polycarbonate), gross lipemia, gross hemolysis, or moderate-to-gross icterus are rejects.
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
4-11 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.4 mL
Minimum Volume
0.2 mL
Container
Polypropylene tube
Collection Instructions
Collect and transport CSF in a polypropylene tube
Storage Instructions
Store frozen
Causes for Rejection
Hemolysis; gross lipemia; specimens collected in glass, polystyrene, or polycarbonate tubes; moderate or gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 5 days |
| Frozen | 31 days |