Alkaline Phosphatase Isoenzymes, CSF
Also known as: CSF ALKP I
Use
The Alkaline Phosphatase Isoenzymes, CSF test is useful in identifying the presence of a heat-stable isoenzyme, such as germ cell or placental, in the cerebrospinal fluid (CSF). This can be of diagnostic relevance for patients with intracranial germ cell tumors, as alkaline phosphatase may be increased in such patients' CSF.
Special Instructions
Refrigerate or freeze the CSF specimen as soon as possible, ideally within 2 hours of collection, to preserve sample integrity and ensure accurate test results. Ensure that the sample is collected in a standard ARUP transport tube and not in any tubes containing EDTA, potassium oxalate, sodium citrate, or sodium fluoride.
Limitations
This test does not quantify the amount of alkaline phosphatase activity. It is designed to detect the presence of heat-stable isoenzymes and cannot provide absolute activity levels. Moreover, specimens that are grossly hemolyzed or lipemic are unacceptable for testing, as are those collected in incorrect anticoagulant tubes.
New York Approved
Methodology
Other
Biomarkers
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP standard transport tube
Storage Instructions
Refrigerate or freeze as soon as possible, ideally within 2 hours.
Causes for Rejection
Specimens collected in EDTA, potassium oxalate, sodium citrate, or sodium fluoride tubes; grossly hemolyzed or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 hours |
| Refrigerated | 1 week |
| Frozen | 1 month |