Protein Electrophoresis With Interpretation With Reflex to IFE, Cerebrospinal Fluid
Also known as: Interpretation, Protein Electrophoresis With Reflex to IFE, CSF, Protein Electrophoresis With Interpretation and Reflex to IFE, CSF
Use
Evaluate for possible multiple sclerosis, subacute sclerosing panencephalitis, and other chronic CNS disorders associated with local IgG synthesis
Special Instructions
The third tube of a routinely obtained three-tube set of CSF should be used for protein electrophoretic study. The stability of the specimen is 3 days refrigerated and 1 month frozen. Ensure proper storage conditions are maintained for accurate results.
Limitations
While protein electrophoresis is a powerful diagnostic tool, its main limitation is that it cannot provide specificity for the type of proteins present beyond their general classification into major protein groups and spikes. For definitive identification of specific proteins, further tests such as immunofixation electrophoresis (IFE) may be necessary if abnormalities are detected. The test also requires proper specimen handling and storage to prevent degradation and ensure accuracy.
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 2880-3
- 13973-3
- 13974-1
- 13972-5
- 13975-8
- 13976-6
- 13977-4
- 12782-9
- 11502-2
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
2 mL
Minimum Volume
1.6 mL
Container
Sterile tube
Collection Instructions
The third tube of a routinely obtained three-tube set of CSF should be used for protein electrophoretic study.
Storage Instructions
Refrigerate at 2°C to 8°C.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 3 days |
| Frozen | 1 month |