Hepatitis C Viral RNA Genotype 1 NS5A Drug-resistance
Also known as: NS5a Drug Resistance
Use
This test detects NS5A resistance-associated variants (RAVs) in genotype 1 hepatitis C virus (HCV), including key codons 28, 30, 31, 58 and 93 (e.g., Y93H), enabling assessment of resistance to NS5A inhibitor direct‑acting antiviral drugs and guiding treatment decisions, particularly for therapy‑naïve genotype 1a patients being considered for NS5A‑containing regimens like elbasvir/grazoprevir or sofosbuvir/ledipasvir. ([questdiagnostics.com](https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq173?utm_source=openai))
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
PCR-based (PCR)
Biomarkers
NS5A
Gene
LOINC Codes
- 82380-7 - HCV Gentyp 1 NS5a Mut Det Islt
- 82379-9 - Daclatasvir Islt Genotyp
- 82377-3 - Ledipasvir Islt Genotyp
- 82378-1 - Ombitasvir Islt Genotyp
- 82376-5 - Elbasvir Islt Genotyp
- 82520-8 - Velpatasvir Islt Genotyp
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
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