Homocysteine
Use
This test measures the level of the amino acid homocysteine in blood. Elevated homocysteine may indicate impaired metabolism and is associated with increased risk of cardiovascular disease, stroke, and blood clots. It may also reflect deficiencies in vitamins B6, B9 (folate), or B12.
Special Instructions
Fasting for 8–12 hours is recommended before collection. No visit to a physician is required to order this test via consumer-initiated services, though an independent healthcare provider oversees the process.
Limitations
Test results may be influenced by vitamin B deficiencies or other conditions; elevated homocysteine may not pinpoint underlying cause and should be interpreted in clinical context.
Methodology
Other
Biomarkers
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1–2 mL
Minimum Volume
0.5–1 mL
Container
Red top (no additive) tube; sodium heparin (green-top) or EDTA (lavender-top) acceptable
Collection Instructions
Separate serum or plasma as soon as possible after clot formation; refrigerate or ice bath for 30 minutes; gel barrier tubes refrigerate only
Patient Preparation
Fasting 8–12 hours recommended
Causes for Rejection
Gross hemolysis; gross lipemia; unseparated serum/plasma; whole blood specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 Days |
| Refrigerated | 14 Days |
| Frozen | 6 Months |