Casandra
Casandra Test Code QD92435Version 1 (DRAFT)
Performing Lab
Lab Quest DiagnosticsLab Test ID 93103
Insulin, Intact, LC/MS/MS
Clinical Use
Order TestUse
The Insulin, Intact, LC/MS/MS assay measures only the intact insulin molecule, avoiding cross‑reactivity with insulin fragments, and is primarily used to evaluate the cause of hypoglycemia. It is particularly useful in assessing hyperinsulinemia and insulin resistance, offering greater specificity than standard immunoassays.
Special Instructions
Not provided.
Limitations
Analytical sensitivity is 3 µIU/mL. The assay has no cross-reactivity with proinsulin or insulin analogs aspart and degludec; however, insulin analogs lispro and glargine may interfere with quantitation. Presence of insulin antibodies may alter results.
Test Details
Methodology
Mass Spectrometry
Biomarkers
Insulin (intact)
AnalyteIntact Insulin • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided