Insulin, Intact, LC/MS/MS
Use
The Insulin, Intact, LC/MS/MS assay measures only the intact insulin molecule, avoiding cross‑reactivity with insulin fragments, and is primarily used to evaluate the cause of hypoglycemia. It is particularly useful in assessing hyperinsulinemia and insulin resistance, offering greater specificity than standard immunoassays.
Special Instructions
Not provided.
Limitations
Analytical sensitivity is 3 µIU/mL. The assay has no cross-reactivity with proinsulin or insulin analogs aspart and degludec; however, insulin analogs lispro and glargine may interfere with quantitation. Presence of insulin antibodies may alter results.
Methodology
Mass Spectrometry
Biomarkers
Insulin (intact)
Analyte
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Other tests from different labs that may be relevant