Casandra
Casandra Test Code QD66292Version 1 (DRAFT)
Performing Lab
Lab Quest DiagnosticsLab Test ID 37523
Neutrophil Function, Oxidative Burst
Clinical Use
Order TestUse
This test, also known as the classic dihydrorhodamine (DHR) 123 assay, assesses neutrophil oxidative burst capability via flow cytometry and is used to aid in the diagnosis of chronic granulomatous disease (CGD) by evaluating the functional integrity of neutrophils' reactive oxygen species generation. It can help distinguish CGD and related conditions by measuring neutrophil responses before and after stimulation.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
Neutrophil Oxidative Index; % Responding Polymorphonuclear Cells
OtherMFI ratio and % responding PMNs
Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
Not provided
Container
heparinized whole blood
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