Casandra
Casandra Test Code QD19559Version 1 (DRAFT)
Performing Lab
RET Sequencing and Deletion/Duplication
Clinical Use
Order TestUse
This test is used to identify individuals with autosomal dominant multiple endocrine neoplasia type 2 (MEN2) syndrome by detecting single‑nucleotide variants, deletions, and duplications in the RET gene, which encodes the proto‑oncogene tyrosine‑protein kinase receptor Ret protein. Clinical indications include individuals with a clinical diagnosis of MEN2 (including MEN2A or MEN2B), medullary thyroid cancer (MTC), and primary C‑cell hyperplasia; informed consent and genetic counseling are strongly recommended.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
NGS (Targeted)
Biomarkers
RET
GeneSNV/Indel
Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Not provided.
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