RPR (Diagnosis) with Reflex to Titer and Treponema pallidum Antibody, IA

Casandra

Casandra Test Code QD27865Version 1 (DRAFT)

Performing Lab

Lab Quest DiagnosticsLab Test ID 36126CPT Code 86592

RPR (Diagnosis) with Reflex to Titer and Treponema pallidum Antibody, IA

Also known as: Syphilis Serology Screen, PR(Dx) rfl Ttr/T.pallidum, Blood Premarital RPR, Automated Reagin Test, ART

Clinical Use

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Use

This is a nontreponemal screening test for syphilis (Rapid Plasma Reagin, RPR). It is used for diagnosis; false-positive results may occur due to conditions such as systemic lupus erythematosus, leprosy, brucellosis, atypical pneumonia, typhus, yaws, pinta, pregnancy, Gaucher disease, old age, or malignancy. Monitoring RPR titers is helpful to assess therapy effectiveness.

Special Instructions

If the initial RPR screen is reactive, then reflex testing is performed automatically: an RPR Titer plus a chemiluminescence Treponema pallidum antibody immunoassay for confirmatory testing will be performed at an additional charge.

Limitations

False-positive RPR results can be associated with infections, pregnancy, autoimmune disease, old age, Gaucher disease, and malignancy. Additionally, false-positive results may reflect other infections (e.g., leprosy, brucellosis, atypical pneumonia, typhus, yaws) or biologic conditions.

Test Details