2,3 Dinor-11Beta-Prostaglandin F2 Alpha, Random Urine
Use
This test is used to screen for mast cell activation disorders like systemic mastocytosis, utilizing random urine specimens. Elevated levels of 2,3-dinor-11beta-prostaglandin F2 alpha (2,3 BPG) may also be observed in patients with angioedema, diffuse urticaria, or myeloproliferative diseases, even in the absence of diffuse mast cell proliferation.
Special Instructions
Not provided.
Limitations
Elevated levels of 2,3 BPG are not specific to systemic mast cell disease and can be present in other conditions such as angioedema and diffuse urticaria. The test's performance characteristics were determined by Mayo Clinic in alignment with CLIA requirements; however, it has not been FDA-cleared or approved.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
2,3 Dinor-11Beta-Prostaglandin F2a
AnalyteCreatinine, Random Urine
Analyte
LOINC Codes
- 2161-8 - Creat Ur-mCnc
- 97658-9 - 2,3-dinor 11B-PG F2a/Creat Ur
Result Turnaround Time
6-11 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL
Minimum Volume
3 mL
Container
ARUP standard transport tubes
Patient Preparation
Discontinue aspirin or NSAIDs 2 weeks or 72 hours respectively, prior to collection.
Storage Instructions
Refrigerated. Also acceptable: Frozen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
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