Bowel Disorders Evaluation Rule-out Cascade
Also known as: Celiac Disease, Gluten Sensitivity, Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS)
Use
This test is intended to aid in the diagnosis of gluten sensitivity in patients with symptoms suggestive of this condition. It can aid in the diagnosis of celiac disease, IBD, differential diagnosis of Crohn's disease (CD) and ulcerative colitis (UC), nonceliac gluten sensitivity and IBS.
Special Instructions
If reflex test is performed, additional charges/CPT code(s) may apply. Testing begins with a celiac screen and cascades through additional steps if initial results are negative. Endoscopy with biopsies remains the gold standard for diagnosis.
Limitations
Results of this profile should be used in conjunction with clinical findings and other laboratory tests. Neither tTG IgA nor DGP IgG strictly confirms or rules out celiac disease. Similarly, the presence of ASCA IgG or atypical pANCA does not confirm IBD.
Methodology
Immunoassay (EIA)
Biomarkers
LOINC Codes
- 31017-7
- 58710-5
- 31017-7
- 58710-5
- 6713-2
- 53029-5
- 20496-6
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Gel-barrier tube, red-top tube or serum transfer tube
Collection Instructions
Specimen should be free of bacterial contamination, hemolysis and lipemia.
Storage Instructions
Room temperature
Causes for Rejection
Hemolysis; lipemia; heat-treated specimen; gross bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant