Engraftment Monitoring, Post
Also known as: Chimerism Testing, Postengraftment Monitoring
Use
Monitor the acceptance of donor cells by the host (recipient) of a stem cell transplant. Polymorphic loci determined in the preëngraftment testing are used for the evaluation.
Special Instructions
To schedule this test, you must telephone HLA customer service at 800-533-1037. It is necessary to ensure that the specimen collection aligns with the specific requirements for engraftment monitoring.
Limitations
This test was developed and its performance characteristics were determined by LabCorp. However, it has not been cleared or approved by the US Food and Drug Administration (FDA). Results are dependent on the quality and quantity of DNA extracted from the specimens. The test is sensitive to detecting donor versus recipient cells at a sensitivity level of 5% or less for typical specimens.
Methodology
PCR-based (PCR)
Biomarkers
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Adult tube
Minimum Volume
3 mL
Container
Lavender-top (EDTA) tube
Storage Instructions
Maintain whole blood at room temperature.
Causes for Rejection
Hemolysis; clotted specimen
Other tests from different labs that may be relevant