Casandra
Casandra Test Code QD78221Version 1 (DRAFT)
Performing Lab
FISH, p53, Deletion 17p13.1
Clinical Use
Order TestUse
This fluorescence in situ hybridization (FISH) assay detects deletion of the TP53 gene region in chromosome 17p13.1. The results of this test may aid in the prognostic assessment and treatment selection for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). The most common genetic abnormalities of CLL/SLL include del(13q), del(11q), trisomy 12, and del(17p).
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Unknown CNV
Copy Number RegionCopy Number Alteration
Copy Number Alteration • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Bone Marrow
Volume
3 mL preferred; 1 mL minimum
Minimum Volume
1 mL
Container
sodium heparin (green‑top) tube
Storage Instructions
Room temperature for most specimens; fresh lymph node refrigerated
Similar Tests
Other tests from different labs that may be relevant
TP53; 17p13 Deletion
MPLN
Vysis Chronic Lymphocytic Leukemia (CLL) Panel
MPLN
Chronic Lymphocytic Leukemia (CLL) Panel
MPLN
Oncology FISH Analysis - CLL FISH Panel
Baylor Genetics
P53 Mutation Analysis
Labcorp
CLL FISH Panel
NeoGenomics
TP53 Mutation Analysis
NeoGenomics
CLL FISH Profile
Labcorp
Oncology FISH Analysis - p53
Baylor Genetics
Chromosome FISH, CLL Panel
ARUP Laboratories