Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA

Casandra

Casandra Test Code AR21249Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0051152CPT Codes 86695, 86696

Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA

Also known as: HERP PAN 2

Clinical Use

Order Test

Use

This test is intended for the serologic diagnosis of herpes simplex viral infection, when the presence of the virus cannot be confirmed by the presence of active lesions. It is useful for identifying individuals who have been exposed to HSV types 1 or 2 and may indicate a current or past infection. Detection is done through IgG antibodies specific to the glycoprotein G of both HSV types, allowing for differentiation between the two.

Special Instructions

This test is New York state approved. Specimens should be collected in a serum separator tube and the serum separated from cells as soon as possible within 2 hours of collection. Parallel testing of acute and convalescent samples is preferred, and convalescent samples must be received within 30 days of the acute sample.

Limitations

Individuals in the early stages of HSV infection may not have detectable IgG antibodies to glycoprotein G of HSV types 1 and 2, which could lead to a negative test result. Additionally, false positive results may occur, especially with results less than or equal to 3.0 IV, necessitating further confirmation through additional testing such as non-type specific assays.

Test Details

FDA Approved