Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG
Also known as: HERPES
Use
The Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG test is used to detect the presence of IgG antibodies against Herpes Simplex Virus Types 1 and 2. This test is mainly utilized to assess previous exposure to the virus and to aid in the diagnosis of herpes infections in conjunction with clinical symptoms and other laboratory tests. Observing changes in antibody titers across paired serum specimens can provide evidence of recent infection.
Special Instructions
Not recommended as a stand-alone test. Parallel testing is preferred, with convalescent specimens needing to be received within 30 days from the receipt of acute specimens. Mark specimens plainly as 'acute' or 'convalescent'.
Limitations
False positive results can occur, particularly if previous infection with other Herpes viruses has occurred. A significant change in antibody levels on two appropriately timed specimens is necessary to confirm current infection. Further testing for HSV-2, especially when results are less than or equal to 3.0 IV, is recommended for more accurate diagnosis.
New York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 27948-9
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP standard transport tube
Collection Instructions
Collect in serum separator tube. Serum from umbilical cord blood is also acceptable.
Storage Instructions
Refrigerated storage is recommended.
Causes for Rejection
Urine, CSF, contaminated, heat-inactivated, icteric, or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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