Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG with Reflex to Type 1 and 2 Glycoprotein G-Specific Ab, IgG

Casandra

Casandra Test Code AR34667Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0051708CPT Codes 86694, 86695, 86696

Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG with Reflex to Type 1 and 2 Glycoprotein G-Specific Ab, IgG

Also known as: HERPR PAN2

Clinical Use

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Use

This test is preferred for detecting herpes simplex virus (HSV) when exposure is suspected. It can be useful in identifying subclinical HSV infections. If results are positive for HSV type 1/2 combined antibodies but negative for both type-specific antibodies, a follow-up test is recommended after at least one month, as glycoprotein antibodies may require 3-6 months to form.

Special Instructions

Parallel testing is preferred. Convalescent specimens must be received within 30 days of acute specimens. Specimens must be clearly marked as 'acute' or 'convalescent.' If HSV 1 and/or 2 IgG is 1.10 IV or greater, then HSV 1 gG-Specific IgG and HSV 2 gG-Specific IgG will be added, with additional charges.

Limitations

False-positive results for HSV antibodies are possible. For the most accurate diagnosis, a significant change should be observed on two appropriately timed specimens, both done at the same laboratory. If the result for HSV-2 is less than or equal to 3.0 IV, additional testing for HSV-2 should be considered.

Test Details

FDA Approved