Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA (Inactive as of 08/19/24)

Casandra

Casandra Test Code AR33305Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0050641CPT Code 86694

Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA (Inactive as of 08/19/24)

Also known as: HSV MC

Clinical Use

Order Test

Use

This test detects IgM antibodies to Herpes Simplex Virus types 1 and/or 2 using an ELISA methodology. However, it is not recommended for diagnostic use since IgM lacks adequate predictive value for acute HSV infection and may produce inaccurate or misleading results. If acute HSV infection is suspected, molecular testing (HSV‑1/HSV‑2 Subtype by PCR, test code 2010095) is preferred.([wellness.riverview.org](https://www.wellness.riverview.org/lab-test/herpes-simplex-virus-type-1-and-or-2-antibodies-igm-by-elisa/?utm_source=openai))

Special Instructions

The test has been discontinued (inactive as of August 19, 2024). Clinical recommendations suggest using molecular PCR testing for acute infection.([lab.parkview.com](https://lab.parkview.com/news-and-updates/news-archives/changes-in-herpes-simplex-virus-testing/?utm_source=openai))

Limitations

IgM tests for HSV are unreliable: they lack specificity between HSV‑1 and HSV‑2, may cross‑react with other viruses, and are prone to false positives and negatives, reducing their clinical utility. IgG testing or molecular testing is preferred.([wellness.riverview.org](https://www.wellness.riverview.org/lab-test/herpes-simplex-virus-type-1-and-or-2-antibodies-igm-by-elisa/?utm_source=openai))

Test Details