Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by CIA
Also known as: HERP I
Use
This test is used to detect the presence of IgG antibodies against HSV type 1 glycoprotein G. A positive result may indicate a current or past infection of HSV type 1. Individuals infected with HSV may not exhibit detectable IgG antibodies to type-specific HSV antigens in the early stages of infection. Detection of antibody presence in these cases might only be possible using a non-type specific screening test. False positives are possible, and additional testing is recommended if results are less than or equal to 3.0 IV for type-specific assays.
Special Instructions
This test is not a stand-alone test and should be ordered in conjunction with the Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by CIA. Glycoprotein antibodies may require 3-6 months to form, so follow-up testing is recommended to confirm negative results in the context of positive HSV Types 1 or 2 antibody results.
Limitations
False positive results are possible. This test may not detect antibodies in the early stages of infection. Consider additional testing for results less than or equal to 3.0 IV for type-specific assays. Detection of antibody presence may only be possible using a nontype-specific screening test.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 42337-6
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Serum separator tube (SST)
Collection Instructions
Allow specimen to clot completely at room temperature. Separate serum from cells as soon as possible or within 2 hours of collection. Transfer serum to an ARUP standard transport tube.
Causes for Rejection
Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |
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