Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by CIA

Casandra

Casandra Test Code AR95424Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0050294CPT Code 86696

Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by CIA

Also known as: HERP II

Clinical Use

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Use

This test is used for the detection of IgG antibodies specific to the glycoprotein G of Herpes Simplex Virus Type 2 (HSV-2). The presence of these antibodies may indicate a current or past HSV-2 infection. In individuals infected with HSV, IgG antibodies to type-specific HSV antigens might not be present in the early stages of infection, and detection of such antibodies may require type-specific assays. False positive results are possible, especially when the results are less than or equal to 3.0 IV, and additional testing might be recommended.

Special Instructions

This test is not a stand-alone test; it should be ordered in conjunction with Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by CIA. Improper handling of samples, such as contamination or hemolysis, can lead to rejection. Correct preparation involves separating the serum from the cells within two hours of collection.

Limitations

Detection of IgG antibodies may not occur in the early stages of infection, resulting in false negatives. Equivocal results may require repeat testing. The test is also prone to false positives, particularly for results under 3.0 IV, recommending further type-specific testing.

Test Details

FDA Approved

New York Approved

Methodology

Immunoassay (CLIA)

Biomarkers

HSV 2 Glycoprotein G Antibody

Protein

HSV 2 Glycoprotein G Antibody, IgG level • Concentration / Level • Ordinal Score (e.g., TPS, CPS, H-score)

LOINC Codes

Order Codes

42338-4

Result Turnaround Time

1-2 days

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

Serum Separator Tube (SST)

Collection Instructions

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube.