Use

Aids in the diagnosis of autoimmune cerebellar ataxia, encephalitis, neuropathy, and myelopathy. May be used to monitor treatment response in individuals who are antibody positive. The presence of ITPR1 antibodies may be associated with cerebellar ataxia, encephalitis with seizures, peripheral neuropathy, and myelopathy. ITPR1 antibody disease may be paraneoplastic, with variable tumor types such as breast, lung, and renal cancers.