Casandra
Casandra Test Code AL92337Version 1 (DRAFT)
Performing Lab
Lab AllelicaLab Test ID N/A
Breast Risk Reveal™
Clinical Use
Order TestUse
Breast Risk Reveal™ is an integrated breast cancer risk assessment combining monogenic variants identified via clinical whole exome sequencing (WES), multi‑ancestry polygenic risk scores (PRS), and established clinical models (e.g., Tyrer‑Cuzick, BOADICEA) to produce a unified lifetime risk estimate for breast cancer that enhances precision and equity across ancestries.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
NGS
Biomarkers
Integration of monogenic variant analysis from clinical whole exome sequencing with multi‑ancestry polygenic risk scores and clinical models, including BOADICEA and Tyrer‑Cuzick, to assess lifetime breast cancer risk.
Mutation (5 genes)
BRCA1BRCA2PALB2CHEK2ATM
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen Requirements
Not provided.