Anti-gp210 Antibody, IgG
Also known as: GP210 AB
Use
GP210 IgG antibodies can be detected in patients with primary biliary cholangitis (PBC) and may be of diagnostic relevance in a subset of patients with PBC who are negative for anti-mitochondrial antibodies (AMA). These antibodies have a relatively low sensitivity with excellent specificity for PBC. A negative result does not rule out PBC.
Special Instructions
Recommended for the evaluation of individuals with suspected primary biliary cholangitis (PBC) who test negative for anti-mitochondrial antibodies (AMA). Sample should be collected and transported according to guidelines to ensure valid results.
Limitations
GP210 IgG antibodies have relatively low sensitivity for PBC, meaning that a negative result does not rule out the disease. However, they have excellent specificity, indicating that a positive result is highly indicative of PBC in the absence of anti-mitochondrial antibodies.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 96560-8
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.1 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Nonserum, heat-inactivated, contaminated, grossly icteric, severely lipemic, grossly hemolyzed specimens, or inclusion of fibrin clot.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month (avoid repeated freeze/thaw cycles) |