Anti-gp210 Antibody, IgG
Also known as: GP210 AB
Use
GP210 IgG antibodies can be detected in patients with primary biliary cholangitis (PBC) and may be of diagnostic relevance in a subset of patients with PBC who are negative for anti-mitochondrial antibodies (AMA). These antibodies have a relatively low sensitivity with excellent specificity for PBC. A negative result does not rule out PBC.
Special Instructions
Not provided.
Limitations
GP210 IgG antibodies have relatively low sensitivity for PBC, meaning that a negative result does not rule out the disease. However, they have excellent specificity, indicating that a positive result is highly indicative of PBC in the absence of anti-mitochondrial antibodies.
Methodology
Immunoassay (ELISA)
Biomarkers
Anti-gp210 Antibody, IgG
Protein
LOINC Codes
- 96560-8 - Nuclear pore prot gp210 Ab Ser IA-aCnc
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.1 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Nonserum, heat-inactivated, contaminated, grossly icteric, severely lipemic, grossly hemolyzed specimens, or inclusion of fibrin clot.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month (avoid repeated freeze/thaw cycles) |
Other tests from different labs that may be relevant
