Primary Biliary Cholangitis (PBC) Profile (RDL)
Use
PBC is an organ-specific autoimmune disease characterized by chronic progressive destruction of small intrahepatic bile ducts with portal inflammation and ultimately fibrosis. PBC affects women more than men and typically occurs between the ages of 30 and 65. PBC affects women more than men and typically occurs between the ages of 30 and 65. The prevalence of PBC in first-degree relatives of PBC patients range is from 1.3 to 6.4%.
Special Instructions
Not provided.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Immunoassay (EIA)
Biomarkers
LOINC Codes
- 106054-0 - PBC comprehensive Ab pnl SerPl
- 42254-3 - ANA Ser Ql IF
- 5247-2 - Mitochondria Ab Titr Ser IF
- 8077-0 - Mitochondria Ab Ser-aCnc
- 96560-8 - Nuclear pore prot gp210 Ab Ser IA-aCnc
- 96565-7 - sp100 Ab Ser IA-aCnc
- 26971-2 - Smooth muscle Ab Ser Ql IF
Result Turnaround Time
8-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
1 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |
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